| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1852519 | Antiproliferative activity against human MV4-11 cells harboring MLL-AF4 assessed as cell growth inhibition measured for 72 hrs by MTT assay | 2022 | Journal of medicinal chemistry, 10-13, Volume: 65, Issue:19
| Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. |
| AID1852538 | Reversible differentiation arrest in human MV4-11 cells at 0.1 to 10 uM measured after 7 days by flow cytometric analysis | 2022 | Journal of medicinal chemistry, 10-13, Volume: 65, Issue:19
| Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. |
| AID1372684 | Binding affinity to menin (unknown origin) by isothermal titration calorimetry | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| Targeting protein-protein interaction between MLL1 and reciprocal proteins for leukemia therapy. |
| AID1372683 | Displacement of FITC-MBM1 from menin (unknown origin) measured after 1 hr by fluorescence polarization assay | 2018 | Bioorganic & medicinal chemistry, 01-15, Volume: 26, Issue:2
| Targeting protein-protein interaction between MLL1 and reciprocal proteins for leukemia therapy. |
| AID1852520 | Antiproliferative activity against human HL-60 cells harboring MLL-AF4 assessed as cell growth inhibition measured for 72 hrs by MTT assay | 2022 | Journal of medicinal chemistry, 10-13, Volume: 65, Issue:19
| Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. |
| AID1231905 | Inhibition of menin-MLL1 interaction (unknown origin) | 2015 | Bioorganic & medicinal chemistry letters, Jul-01, Volume: 25, Issue:13
| Progress towards small molecule menin-mixed lineage leukemia (MLL) interaction inhibitors with in vivo utility. |
| AID1852518 | Inhibition of Menin/fluorescein labeled MLL(4 to 43 residues) (unknown origin) protein protein interaction incubated for 1 hr by fluorescence polarization-based competitive binding assay | 2022 | Journal of medicinal chemistry, 10-13, Volume: 65, Issue:19
| Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. |
| AID1852539 | Induction of apoptosis in human MV4-11 cells incubated for 24 hrs by annexinV/PI staining based flow cytometry analysis | 2022 | Journal of medicinal chemistry, 10-13, Volume: 65, Issue:19
| Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. |
| AID1852537 | Induction of cell differentiation in human MV4-11 cells assessed as increase in CD11b expression at 10 uM measured after 7 days by flow cytometric analysis | 2022 | Journal of medicinal chemistry, 10-13, Volume: 65, Issue:19
| Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. |
| AID1852523 | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability measured for 3 days followed by replacement with fresh medium of compound and measured after 72 hrs by cell counting assay | 2022 | Journal of medicinal chemistry, 10-13, Volume: 65, Issue:19
| Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. |
| AID1416307 | Inhibition of menin (unknown origin)-FITC-tagged MLL1 (unknown origin) protein-protein interaction after 1 hr by fluorescence polarization assay | 2017 | MedChemComm, Dec-01, Volume: 8, Issue:12
| Theoretical models of inhibitory activity for inhibitors of protein-protein interactions: targeting menin-mixed lineage leukemia with small molecules. |
| AID1852522 | Antiproliferative activity against human MV4-11 cells assessed as reduction in cell viability measured for 3 days by cell counting assay | 2022 | Journal of medicinal chemistry, 10-13, Volume: 65, Issue:19
| Discovery of Novel, Potent, and Selective Small-Molecule Menin-Mixed Lineage Leukemia Interaction Inhibitors through Attempting Introduction of Hydrophilic Groups. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |